Predictive approaches play an important role in detecting events, controlling risks and reducing maintenance and repair costs.The purpose is to provide a model for predicting critical and prioritized risks based on data mining algorithms.Data mining method was planned based on the CRISP methodology.Data modeling has been done in two parts: "descrip
Helper NLR immune protein NRC3 evolved to evade inhibition by a cyst nematode virulence effector.
Parasites can counteract host immunity by suppressing nucleotide binding and leucine-rich repeat (NLR) proteins that function as immune receptors.We previously showed that a cyst nematode virulence effector SPRYSEC15 (SS15) binds and inhibits oligomerisation of helper NLR proteins in the expanded NRC1/2/3 clade Tablecloth by preventing intramolecul
Culling the Herds? Regional Divergences in Rinderpest Mortality in Flanders and South Holland, 1769-1785
The cattle disease rinderpest devastated Europe throughout the eighteenth century.The practice of preventative slaughter, or stamping out, has been seen as the most effective method of containing the disease.Historians frame this strategy as a measure of the effectiveness of centralized bureaucracy in handling epidemic outbreaks.The Austrian Nether
Preclinical and clinical trials of oncolytic vaccinia virus in cancer immunotherapy: a comprehensive review
Oncolytic virotherapy has emerged as a promising Toys Pretty Love treatment for human cancers owing to an ability to elicit curative effects via systemic administration.Tumor cells often create an unfavorable immunosuppressive microenvironment that degrade viral structures and impede viral replication; however, recent studies have established that